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After stratification by histological subtype, a significantly increased frequency of the GSTM1 null genotype was only observed for endometrioid (65%, P = 0.013) and combined endometrioid/clear cell ovarian cancers (67%, P = 0.004)

Based on this finding, the most recent 2018 recommendations from the American Diabetes Association state that compared with basal-plus insulin, basal insulin plus GLP-1 RAs are associated with less hypoglycemia and with weight loss instead of weight gain but may be less tolerable and have a greater cost [2]

Most Medicare and insurance plans cover these medications when prescribed to treat Type 2 diabetes

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